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doi: 10.1073/pnas.1910073116 224 ZhangSYuDWangMHuangTWuHZhangYet al
[6] The good news is that this worst-case scenario is extremely rare, and with the right habits, constipation can usually be prevented or kept under control
More significant changes in fine lines and firmness generally require 8-12 weeks of consistent use
Patients with a BMI of 40 kg/m or greater, or 35 kg/m or greater with significant comorbidities, may be referred to specialist tier 3 or tier 4 weight management services, depending on local pathways
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